What are the benefits of using matched PDX pairs for my preclinical study?

A matched-pairs approach can reduce variability between early and definitive preclinical studies and may lead to better translation of preclinical data to the clinic. Proprietary patient-derived xenograft 3D cell cultures can be used for early screening investigations and hypothesis generation. When you are ready, move seamlessly into the matched PDX in vivo model, or continue using the PDX-derived cell cultures in vivo.