There are many new and emerging technologies in the field of precision oncology (genomic profiling, in silico modeling and others) that can give insight into what therapies might fight your cancer. In fact, these directional tools are complementary to YourPDX Functional Precision Oncology testing because they may help determine which therapies we should test in the cancer patient’s individual clinical research study. Beyond genomics, YourPDX testing is an advanced functional approach to precision oncology that has been shown to closely mimic the tumor microenvironment, metastatic behavior and drug response.1-4
References: 1 Das Thakur, M., Salangsang, F., Landman, A. et al. Modeling Vemurafenib Resistance in Melanoma Reveals a Strategy to Forestall Drug Resistance. Nature. 2013; 494(7436): 251–255. 2 Walters DM, Stokes JB, Adair SJ, et al. Clinical, Molecular and Genetic Validation of a Murine Orthotopic Xenograft Model of Pancreatic Adenocarcinoma Using Fresh Human Specimens. PLoS One. 2013;8(10): e77065. 3 Killion JJ, Radinsky R, Fidler IJ. Orthotopic Models are Necessary to Predict Therapy of Transplantable Tumors in Mice. Cancer Metastasis Rev. 1998-1999;17(3):279–284.
2013;8(10): e77065. 4 Qiu W, Su GH. Development of Orthotopic Pancreatic Tumor Mouse Models. Mol Biol. 2013; 980: 215-223.