No, genetic sequencing is not required for YourPDX Functional Precision Oncology testing. However, genetic/molecular profiling data may provide directional information about what targeted therapies to test. Also, with CertisAI, we can use tumor RNA sequencing data from a patient’s tumor to predict an individual’s response to both monotherapies and combination therapies. These predictions can inform YourPDX study design and provide oncologists with additional therapeutic options to consider.