How do Certis scientists know what therapeutic dose to administer in the mice, given the fact that they are so tiny?

An important part of your study design involves Certis scientists carefully formulating test agents by scaling human treatment regimens into mouse-appropriate doses. Researchers have been studying drug response in mice for decades, so there is an abundance of peer-reviewed scientific literature to guide us when making these decisions.¹

1 Lee, M.W., Miljanic, M., Triplett, T. et al. Current Methods in Translational Cancer Research. Cancer and Metastasis Reviews, 40, 7–30 (2021).