Yes, YourPDX can be used to test drug sensitivity for patients with advanced metastatic cancers. With the right treatment, many metastases can be effectively controlled for years. By modeling metastatic patterns, functional assays using patient-derived xenograft orthotopic models can give new hope to patients with advanced metastatic cancers.1,2
References: 1 Walters DM, Stokes JB, Adair SJ, et al. Clinical, Molecular and Genetic Validation of a Murine Orthotopic Xenograft Model of Pancreatic Adenocarcinoma Using Fresh Human Specimens. PLoS One. 2013;8(10): e77065. 2 Killion JJ, Radinsky R, Fidler IJ. Orthotopic Models are Necessary to Predict Therapy of Transplantable Tumors in Mice. Cancer Metastasis Rev. 1998-1999;17(3):279–284.